The C Diff Foundation, the leading Patient and Healthcare Global Organization Educating and Advocating for C. difficile (Clostridioides difficile, C. diff., CDAD, CDI) infection prevention, treatments, clinical trials, diagnostics, support, and environmental safety worldwide.  The Foundation is a  501(c) (3)  a non-profit organization, established in 2012. This organization is comprised of 100% volunteering professionals dedicated to supporting public health through education and advocating for C. difficile infection (also known as C. diff.,
C. difficile, CDAD, CDI) prevention, treatments, clinical trials, environmental safety worldwide.

There are many avenues connected to C. difficile infections which lead
the C Diff Foundation Members and Volunteer Patient Advocates down adjacent roads raising awareness of antibiotic-resistance, antibiotic stewardship programs, Sepsis, COVID-19, and a multitude of general wellness topics with fellow Government, Medical Provider, and Cause-specific organizations; MD mag, Sepsis Alliance, CDC, Global Sepsis Alliance to name a few.

The Foundation’s founder is a Nurse and after suffering through C. difficile infections herself and witnessing the loss of her father whose life was claimed by C. difficile involvement, the
C Diff Foundation came to fruition.  The C Diff Foundation Members, with  their
Volunteer Health Advocates, successfully “Raise C. diff. Awareness”  nationwide and have touched lives in fifty-six countries.    There is a U.S. Nationwide information Hot-Line (1-844-FOR-CDIF) to support health care providers, patients, families, and caregivers to manage  through all of  the difficulties associated with a C. diff. infection.  There are a variety of patient/family, and healthcare provider programs available to provide information and support.

An excerpt from a USA Today article published in 2012:    Deaths and illnesses are much higher than reports have shown. In March, the  CDC  said in a report that the C difficile infection kills 14,000 people a year. But that estimate is based on death certificates, which often don’t list the infection when patients die from complications, such as kidney failure.  Hospital billing data collected by the federal Agency for Healthcare Research and Quality shows that more than 9% of C. diff-related hospitalizations end in death — nearly five times the rate for other hospital stays. That adds up to more than 30,000 fatalities among the 347,000 C. diff hospitalizations in 2010. Thousands of more patients are treated in nursing homes, clinics, and doctors’ offices.

C. difficile is one of the most common causes of health care- associated infections in U.S. hospitals (Lessa, et al, 2015, New England Journal of Medicine). Recent estimates suggest
C. difficile approaches 500,000 infections annually in the U.S. and is associated with approximately 20,000 deaths annually. (Guh, 2020, New England Journal of Medicine). Based on internal estimates, the recurrence rate of two of the three antibiotics currently used to treat CDI is between 20% and 40% among approximately 150,000 patients treated. We believe the annual incidence of CDI in the U.S. approaches 600,000 infections and has a mortality rate of approximately 9.3%.

“We’re talking in the range of close to 500,000 total cases a year,” says Cliff McDonald, a C. diff expert, and senior science adviser in the CDC’s Division of Healthcare Quality Promotion. And annual fatalities “may well be … as high as 30,000.”

* AHRQ News and Numbers provides statistical highlights on the use and cost of health services and health insurance in the United States.


This is sound evidence and gives a concrete reason why the C Diff Foundation continues with the  Mission in Educating and advocating for C difficile infection prevention, treatments, and environmental safety worldwide.

The continued global support of the C Diff Foundation’s mission is through collaborative efforts from healthcare providers, the general public, medical healthcare organizations, healthcare professionals, government agencies, villages to communities, which will result in positive results in the reduction of newly diagnosed Clostridium difficile cases and preventable deaths.   In the USA:  Nearly half a million Americans suffer from Clostridium difficile (C. diff.) infections in a single year according to a study released February 25, 2015, by the Centers for Disease Control and Prevention (CDC). **Approximately 29,000 patients died within 30 days of the initial diagnosis of C. difficile.  Of those, about 15,000 deaths were estimated to be directly attributable to C. difficile infections (CDI), making C. difficile a very important cause of infectious disease death in the United States.  More than 80 percent of the deaths associated with C. difficile occurred among Americans aged 65 years or older. C. difficile causes an inflammation of the colon and deadly diarrhea.

The Foundation’s mission is dedicated to reaching out to communities from villages to cities, to medical practitioners, medical students, C. diff. survivors, caregivers, and the patients combating a  C. diff.  infection (CDI) while providing the general public important information on prevention, treatments available, and EPA registered products available for environmental safety. We continue moving forward setting up outreach centers and building positive networks with the C Diff Foundation  Volunteer Health Advocates aiding in promoting  C. diff. awareness worldwide.

If you have questions and would like to register to join the C Diff Foundation Volunteer Program or wish to help us extend the outreach of the C Diff Foundation please contact us:

Office Hours: 900 a.m. to 4:00 p.m. EST, Monday-Friday

Office #: 1 – (727) – 205-3922

EMAIL:   info@cdifffoundation.org



C Diff Foundation Board of Directors

Nancy C Caralla, Founding President, Executive Director,
Scott Battles, Vice President
Dr. Ahmed A. M. Al Mandalawi, MD, Medical Director
Tony DelMonaco,  Secretary
Angelo Ortiz, Treasurer


C Diff Foundation Chair and Committees




Research and Development Committee
Dr. Simon Cutting, MS, Ph.D., Chairperson
Dr. Martha R. Clokie, MS, PhD
Dr. Norman Javitt, MD
Dr. Kerrie Davies, PhD

Medical Advisory Board
Dr. Mark Wilcox, MD, Chairperson
Dr. Barbara McGovern, MD
Dr. Sahil Khanna, MD

C. diff. Global Community Support Program
Dr. Paul Feuerstadt, MD, Co-Director
Dr. Caterina Oneto, MD, Co-Director
Scott Battles –  Support Leader
Karen Factor, RD-  Support Leader

C Diff Foundation Volunteer Health Advocate Program
Angelo Ortiz, Chairperson
Kathy & David Bischoff, Coordinators

Administrative Support Committee
Josh Factor, Fundraising/Grant Writing Development Coordinator
Scott Bauer, Administrative Support Intern
Jennifer Boyle, Office Support

Global Community Education & Outreach Programs
Paul Feuerstadt, MD, FACG, AGA-F  – Director of Medical Education

Triage Program
Linda Davis, BSN, RN-BC – Triage Coordinator

Global TeleSupport Network Committee
Paul Feuerstadt, MD, FACG, AGA-F – Co-Director
Caterina Oneto, MD – Co-Director

Nutrition and Wellness Committee
Karen Factor, RD, MS, Chairperson
Michele Martello, Wellness Advocate

Junior Infection Fighters Program
Dayle Skelly, Program Director
Teena Chopra, MD, MPH, FACP, FIDSA, FSHEA, Co-Director Infection Prevention Education
Maureen Spencer, M.Ed, BSN, RN, CIC, FAPIC, Co-Director Infection Prevention Education

Infectious Diseases Committee
Nicola Petrosillo, MD, Chairperson
Glenn Tillotson, Ph.D., Co-Chairperson
Barley Chironda, RPN, CIC, Infection Prevention Advocate
Ron Romano, RN, Infection Prevention Advocate
Dr. Rosie Lyles, MD, Infection Prevention Advocate


Main Office:  8520 Government Drive, Suite 1,   New Port Richey, FL 34654  USA

Phone:           (727) – 205 – 3922

Fax:                (727) – 205 – 3923

Email:             info@cdifffoundation.org