New Drug Formulations by a Team of Five Researchers in Singapore Fighting Respiratory Infections and Antibiotic-Resistant Superbugs

In the news:

A team of five researchers and clinicians in Singapore led by Dr Desmond Heng, ICES, has developed a new combination of drugs to effectively combat bacteria in the lungs which lead to common respiratory system infections, or bacteria-linked pulmonary diseases such as pneumonia, bronchiectasis and cystic fibrosis.

An acute upper respiratory tract infection, which includes the common flu, was reported to be among the top four conditions diagnosed at polyclinics for eight consecutive years, from 2006 to 2013.

Pneumonia on the other hand, was the second leading cause of death in 2012, contributing to 16.8 per cent of the total number of deaths from illnesses behind cancer.

The team has developed four new drug formulations of  antibiotics  and muco-actives which have proven to be extremely effective in laboratory trials in treating these diseases, as well as in reducing the antibiotic resistance of so-called “superbugs”.

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