Tag Archives: Emory University School of Medicine

Seeking Patients Who Have Had Three or More Recurrences With a C. difficile Infection



3 April 2014

Dr. Tanvi Dhere, MD and Dr. Colleen Kraft, MD at Emory University are currently working with a company testing a set of encapsulated fecal transplants (to swallow) for treatment of recurrent C. difficile infection.  

The first phase (15 patients) has been completed and patients showed a good response.  The delivery is ideal for many patients with C. difficile infection who are elderly and with multiple comorbidities who may have difficulty with colonoscopy.  

We are looking for patients who are on their third or more recurrence of C. difficile infection.

Patients with inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS) are ineligible.

 If you have any potential patients, please have them contact Dr. Colleen Kraft at 404-712-8889 (USA) or email:   colleen.kraft@emory.edu.

*Patients please contact Dr. Colleen Kraft directly via: email for additional information and consideration.  Also,  participants must be willing to travel to Atlanta for 4 study visits

Thank you.

Photo courtesy of E. Ford



Fecal Transplant Pill Introduced

Clearly a true innovative treatment for the recurrence of C. diff.. During IDWeek 2013, taking place in San Francisco, California, Canadian authors presented the new study and first formal success of fecal transplant pills treating the recurrence of C. diff. infections.

Dr. Thomas Louie, an infectious disease expert from the University of Calgary, found a way to package donated stool into vitamin-sized capsules used to repopulate the intestines of C. diff sufferers with beneficial bacteria. Dr. Louie has treated 27 patients and none had a recurrence of C. diff, even though all of them had had at least four bouts of the infection, which can lead to severe disease or death.

Quoted from the article:
Fecal transplant experts at the University of Minnesota have had some success with freezing fresh stool, and some suggest that freeze-drying the organisms might be a way to preserve it for wider use. Dr. Cliff McDonald, a C. diff expert at the CDC, said Louie’s work represents further innovation in the potentially life-saving treatment for the infections. “The idea has been held by a few for a number of years, but no one else I am aware of is actually doing it this way other than Dr. Louie,” he said.

Dr. Colleen Kraft, who performs fecal transplants at the Emory University School of Medicine, agreed.
“This is clearly the future of fecal transplant therapy,” she told NBC News. “And there are many poised in the market to support this type of therapy and related synthetic bacteriotherapy. I do not see any drawbacks if it is indeed efficacious.”

To read this article in its entirety please click on the link below: