Monthly Archives: January 2014

Clostridium difficile: RI Hospital researchers identify components of C. diff for a possible rapid diagnostic test

Microscope - 5Dr. Leonard Mermel, DO, Medical Director of Epidemiology and Infection Control at Rhode Island Hospital, along with research colleagues, identified components in Clostridium difficile that could possibly advance to the development of a rapid lab - diagnostic test. This study will pave way to a new tool that will enable clinicians, especially in both Emergency departments and Urgent Care settings, the ability to rapidly diagnose a patient displaying symptoms of an active C. dfif. infection. The rapid test results will provide an accurate diagnosis, prompt treatment, with hopes of decreasing severe complications associated with a C. diff. infection.

Dr. Leonard Mermel, DO, Medical Director of the Department of Epidemiology and Infection Control at Rhode Island Hospital with academic appointment at The Warren Alpert Medical School of Brown University, along with research colleagues; Stephanie L. Angione, Anubhav Tripathi of the Center for Biomedical Engineering at Brown University, Aleksey Novikov, MD, and Jennifer Fieber of Brown University, and Aartik A. Sarma of Harvard Medical School.

http://www.eurekalert.org/pub_releases/2014-01/l-rhr013014.php

Maintaining Hydration + Nourishment during a Clostridium Difficile infection

soupchicken3Our bodies depend on water and every cell, tissue and organ depends upon water to operate efficiently. The body uses water to maintain temperature, remove waste, and lubricate joints and water makes up for more than half of our body weight. When it comes to hydration water is the best option. There are other fluids and foods that can aid in providing water needed. Fruit and vegetable juices, broths, milk, sports drinks can contribute to the amount of water you should get each day. Limiting caffeinated beverages is recommended as caffeine may cause fluid shifts from body tissue to intestines promoting elimination and some to urinate more frequently, create anxious or jittery symptoms. A moderate amount of caffeine, 200 to 300 milligrams, equivalent to 2 to 4 eight-ounce cups of a caffeinated beverage per day. Water rich foods such as watermelon, tomatoes and lettuce can aid in warding off dehydration.

Is your body low on water?

You lose water each day when you go to the bathroom, sweat, and even when you breathe. Water is lost from the body even faster when combating an infection or being out in the hot weather. Individuals exercising in hot weather, ill with a fever,or vomiting and having bouts of diarrhea are at a higher risk of dehydration. The elderly are also at a higher risk of dehydration due to decreased senses that contribute signaling the body of the feeling of thirst. When the lost fluids are not replaced, dehydrated occurs. Offering fluids frequently to older individuals will aid in maintaining hydration. Monitoring urine color during the day is another way to know if the body is well hydrated: When the urine is colorless to a light yellow in color hydration is being maintained. If the urine is dark yellow in color, the body is in need of additional fluids. How much is enough? The average daily intake required for a healthy body is 8 eight ounce glasses of fluids a day. There are various circumstances for each individual. Individuals diagnosed with heart conditions (i.e., Congested Heart Failure, etc.) may be instructed by their health care providers to limit fluids in their daily diet. Patients diagnosed with altered kidney functions will also be placed on their own daily fluid intake program. Discussing your daily fluid intake, with your physician or professional health care provider, is suggested.

What are some symptoms of dehydration? Little or no urine, with a urine color that is of dark yellow, Dry mouth, Sleepiness or fatigue, Extreme thirst, Headache, Confusion, Feeling dizzy or lightheaded, No tears when crying

It can be very difficult to recognize dehydrated, especially in the elderly. Preventing dehydration by drinking plenty of water, and following your health care providers recommendations, can prevent dehydration.

If you are unable to maintain hydration for any reason, seek medical attention as soon as possible.

Contact your Primary care physician to report symptoms and/or visit a local clinic/hospital for medical care.

A quick and easy recipe for Chicken, Zucchini, and Spinach Soup to maintain hydration and help stay nourished.

Total prep time: 60 minutes

Ingredients: 2 Chicken breasts, 4 cups broth of choice (Vegetable, Chicken, Beef), 4 cups water, 1 large zucchini, 1 yellow onion, 1 Tomato diced, 1 bag of fresh or frozen spinach, 2 cloves minced garlic, 3/4 cup Tomato sauce.

In a large stock pot add the water, broth, and the two chicken pieces. Bring to a boil then reduce to a simmer allowing the chicken to cook thoroughly (approx. twenty minutes). After twenty minutes remove the chicken from the broth and cut the chicken into cubes. While broth is simmering add chicken cubes back into the stock pot and continue to cook on medium/low heat. Chop the zucchini, onion, and tomato into small cubes and add them into the stock pot, stir in the spinach, garlic, and tomato sauce. Cover and cook for fifteen to twenty minutes for vegetables to cook. *Options: In a separate pot boil water for pasta egg noodles, or rice, or orzo to be served with the vegetable soup. This is a low fat recipe. Sodium content can be controlled by choosing a low-sodium broth. Salt and Pepper to taste. Buon appetito.

Rebiotix, Inc. Completes Enrollment in Phase II Clinical Trial

In The News:

Rebiotix Inc. has announced that it has completed enrollment in the PUNCH CD Phase 2 clinical trial of RBX2660 (microbiota suspension) for the treatment of recurrent Clostridium difficile-associated diarrhea (CDAD). The study is the first of its kind prospective, multi-center clinical study to evaluate a non-antibiotic, live microbial drug product for the treatment of recurrent CDAD conducted using the same protocol at all sites.

To read the article in its’ entirety please click on the following link:

http://finance.yahoo.com/news/rebiotix-completes-enrollment-phase-2-142400625.html?soc_src=mediacontentstory

C. diff. and bacteria; Researchers recommend disinfecting the computer tablets

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A new study conducted by research infectious disease specialists in North Dakota have confirmed how germs and harmful bacteria are being carried around on computer devices. Alcohol wipes proved effective to remove Methicillin-Resistant Staphylococcus Aureus bacteria, however; the Clostridium difficile (C. diff.) bacterial spore requires bleach products to kill and remove them from surfaces.

Acrylic or plastic screen protectors may be the answer to be able to utilize disinfectants that kill and remove the Clostridium difficile (C. diff.) spores amongst other harmful bacteria lingering on these and similar computer devices. *Always check with the product manufacturer prior to using any disinfecting product.

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Restricting mobile devices in the Isolation Rooms is a positive way to prevent the spreading of germs. In settings where mobile devices are being shared (i.e., schools, libraries, healthcare settings, etc.) using disposable
electronic tablet covers purchased in bundles of ten is recommended by Dr. Dubert Guerrero
Infectious Disease specialist at Sanford Health.

To read more about Dr. Guerrero, and his colleagues research results, please click on the following link:

http://www.inforum.com/event/article/id/422797/