Norepinephrine has long been the stable pressor agent for sepsis, but new data suggest that vasopressin might offer unique benefits. In this “150 Second Analysis”, MedPage Today clinical reviewer F. Perry Wilson discusses a study pitting the two drugs head-to-head, with an eye on renal failure as the primary outcome.
F. Perry Wilson, MD, MSCE, is an assistant professor of medicine at the Yale School of Medicine. He earned his BA from Harvard University, graduating with honors with a degree in biochemistry. He then attended Columbia College of Physicians and Surgeons in New York City. From there he moved to Philadelphia to complete his internal medicine residency and nephrology fellowship at the Hospital of the University of Pennsylvania. During his post graduate years, he also obtained a Master of Science in Clinical Epidemiology from the University of Pennsylvania. He is an accomplished author of many scientific articles and holds several NIH grants. He is a MedPage Today reviewer, and in addition to his video analyses, he authors a blog, The Methods Man. You can follow @methodsmanmd on Twitter.
Dr. Hudson Garrett, Jr. PhD, MSN, MPH, FNP, CSRN, VA-BC, CDONA,FACONA,DON-CLTC , C-NAC , PLNC
In this episode Sepsis will be defined by three Healthcare Clinicians and one Clinician — a Sepsis survivor. According to the CDC’s National Center for Health Statistics estimates that, based upon information collected for billing purposes, the number of times people were in the hospital with sepsis or septicemia (another word for sepsis) increased from 621,000 in the year 2000 to 1,141,000 in 2008. Between 28 and 50 percent of people who get sepsis die.
Sepsis is a potentially life-threatening complication of an infection. If sepsis progresses to septic shock, blood pressure drops dramatically, which may lead to death. Anyone can develop sepsis, but it’s most common and most dangerous in older adults or those with weakened immune systems. Early treatment of sepsis improves chances for survival.
MORE ABOUT OUR GUESTS:
Carl Flatley, DDS, MSD
On April 30, 2002, Carl Flatley’s life changed. It was the day his daughter
Erin died from Septic shock, something Dr. Flatley, a retired Endodontist,had never heard of.
After Erin’s death, Dr. Flatley learned everything he could about sepsis and he was
astounded at what he – and millions of other Americans – didn’t know about the condition.
He was shocked to learn that sepsis killed well over 200,000 people in the U.S. every year
and affected so many more survivors. In 2004, Dr. Flatley founded the American Sepsis Alliance,which in 2007,became Sepsis Alliance. He made it his mission that sepsis would become as well known as cancer, diabetes, and other illnesses, and that as few people as possible would get sepsis, let alone die from it. His unending devotion to Erin’s memory has had a significant impact on many people.
Sherrie Dornberger, RN,CDONA, GDCN, CDP, CADDCT, FACDONA Clinician and Sepsis Survivor
NADONA/LTC is a Nurse specialty organization representing the nurse leaders within the long term care continuum association with a mission to support and promote quality of care for those individuals receiving long term care, and concern for those delivering long term care. NADONA/LTC has nominated Sherrie Dornberger as their designated representative. Sherrie is the current Executive Director of NADONA/LTC, and is a Registered Nurse with 40+ years of experience in Nursing Administration, Long Term Care, and Infection Prevention.
Hudson Garrett, Jr. PhD, MSN, MPH, FNP, CSRN, VA-BC, CDONA,FACONA,DON-CLTC , C-NAC , PLNC
Dr. Garrett is a recognized international expert in infection prevention and control.
Dr Garrett currently serves as the Chairperson of the Education Committee for the
C Diff Foundation, and Vice President, Clinical Affairs PDI, Inc. and is a graduate of the
Johns Hopkins Fellows Program in Infection Control and Hospital Epidemiology. He was honored as a Who’s Who for Infection Control by Infection Control Today Magazine in 2013 in recognition of his contributions to the field.
“C. diff. Spores and More “ Global Broadcasting Network spotlights world renowned topic experts, research scientists, healthcare professionals, organization representatives,C. diff. survivors, board members, and their volunteers who are all creating positive changes in the
C. diff. community and more.
Through their interviews, the C Diff Foundation mission will connect, educate, and empower many worldwide.
Questions received through the show page portal will be reviewed and addressed by the show’s Medical Correspondent, Dr. Fred Zar, MD, FACP, Dr. Fred Zar is a Professor of Clinical Medicine, Vice Head for Education in the Department of Medicine, and Program Director of the Internal Medicine Residency at the University of Illinois at Chicago. Over the last two decades he has been a pioneer in the study of the treatment of Clostridium difficile disease and the need to stratify patients by disease severity.
Access this program Podcast on C. diff. Spores and More Global Broadcasting Network by clicking on the logo above *
“Sepsis – Number One Preventable Cause of Death Worldwide”
On Tuesday, April 5th our guests Dr. Niranjan “Tex” Kissoon and Sepsis Survivor Ray Schachter discussed Sepsis – Number One Preventable Cause of Death Worldwide.
In this episode Tex Kissoon, MD,a well-known physician from Canada, provided us with the insight into the global phenomenon of Sepsis. Sepsis affects more than 30 million lives per year yet it is almost unknown to the general public and is quite often misdiagnosed by medical professionals worldwide. The reasons of why that is with the “why” Sepsis is so deadly, and what you can do to increase Sepsis awareness– were discussed in 60 minutes. Dr. Kissoon was joined by Ray Schachter, a Sepsis survivor who now dedicates all of his available time raising awareness of Sepsis worldwide. Both guests are members of the Global Sepsis Alliance (GSA), which has established World Sepsis Day on September 13thevery year to raise awareness for Sepsis worldwide.
About Our Guests:
Dr. Niranjan “Tex” Kissoon, MD
Dr. Kissoon is the Past President of the World Federation of Pediatric Critical and Intensive Care Societies, Vice-President, Medical Affairs at BC Children’s Hospital and Professor, Pediatric and Surgery (Emergency Medicine) Department of Pediatrics at the University of British Columbia in Vancouver, BC as well as he holds the University of British Columbia BC Children’s Hospital (UBC BCCH) Endowed Chair in Acute and Critical Care for Global Child Health. Dr. Kissoon is the vice chair of the Global Sepsis Alliance, co-chair of World Sepsis Day and the International Pediatric Sepsis Initiative.). He has been involved in both advocacy and in promoting Canada-wide involvement in World Sepsis Day as part of a global initiative. He is also involved in promoting sepsis guidelines such that appropriate treatments are given even in areas where there are limited resources.
Dr. Kissoon was awarded a Distinguished Career Award by the American Academy of Pediatrics in 2013 for his contribution to the society and discipline as well as the prestigious Society of Critical Care Medicine’s (SCCM) Master of Critical Care Medicine award in 2015 in recognition of his tireless efforts and achievements as a prominent and distinguished leader of national and international stature. He was also awarded the BNS Walia PGIMER Golden Jubilee Oration 2015 Award for major contribution to Pediatrics in India from the Postgraduate Institute Medical Education and Research.
A Direct Quote From Our Guest and Sepsis Survivor; Ray Schachter:
“I miraculously survived acute Sepsis in 1996 due to extensive medical intervention and have experienced the immediate and long-term consequences on me and my family. I am the Chair of the Global Sepsis Alliance (GSA) Task Force whose goal is to have the UN mandate Sepsis as a World Health Day. Working with these very accomplished and committed people from GSA, many of whom are on the GSA Executive or Ambassadors, on this important project is a very special opportunity.”
About The Global Sepsis Alliance (GSA):
Sepsis is one of the most underestimated health risks. It affects more than 30 million people worldwide each year; for 6 to 8 million of them with a fatal outcome. Surviving patients often suffer for years from late complications.
This is all the more disturbing as sepsis incidence could be considerably reduced by some simple preventive measures such as vaccination and improved adherence to hygiene standards, early recognition and optimized treatment. The main danger of sepsis results from a lack of knowledge about it.
The founding members of the Global Sepsis Alliance (GSA) have recognized the need to elevate public, philanthropic and governmental awareness and understanding of sepsis and to accelerate collaboration among researchers, clinicians, associated working groups and those dedicated to supporting them. For this reason, they initiated the Global Sepsis Alliance in 2010. Together with supporting organizations from across the globe, we are united in one common goal:
The GSA wants to ensure that:
The incidence of sepsis decreases globally by implementation of strategies to prevent sepsis.
Sepsis survival increases for children (including neonates) and adults in all countries through the promotion and adoption of early recognition systems and standardized emergency treatment
Public and professional understanding and awareness of sepsis improve
Access to appropriate rehabilitation services improve for all patients worldwide
The measurement of the global burden of sepsis and the impact of sepsis control and management interventions improve significantly
The GSA Current priorities:
Acknowledgement of a resolution on sepsis including official designation of World Sepsis Day (WSD) as one of the World Health Days by the World Health Assembly.
Recognition of sepsis in the Global Burden of Disease Report
Increase of public awareness and implementation of quality improvement initiatives
Today, we are glad to inform you that Achim Steiner, Under-Secretary-General of the United Nations, Executive Director of the United Nations Environment Programme and designated new director of the Oxford Martin School, made his very inspiring keynote lecture held at the German National Academy of Sciences meeting “Sepsis – The Challenges of Science, Politics and Society” available to all of us.
In his keynote address, he clearly states that tackling sepsis is crucial to more than half of the 17 goals of the 2030 agenda for sustainable development!
This agenda was adopted by the UN Sustainable Development Summit in September 2015 and aims to end poverty and hunger, improve health and education, make cities more sustainable, combat climate change and protect oceans and forests.
We highly encourage you to share this link with your families, friends, and co-workers!
Thank you for your continued support and warm regards from Germany,
Prof. Konrad Reinhart, MD, ML
World Sepsis Day is a concept developed by the Global Sepsis Alliance, and operated as a collaborative effort with other relevant parties Global Sepsis Alliance The Global Sepsis Alliance is a charity registered in England and Wales number 1142803 and a company limited by guarantee, registered in England and Wales number 7476120
Head office: Global Sepsis Alliance for the World Sepsis Day: Center for Sepsis Control and Care Prof. Konrad Reinhart, MD, ML Erlanger Allee 101 07747 Jena Germany Fon: +49 3641 / 9323101 Fax: +49 3641 / 9323102 Email: firstname.lastname@example.org