Tag Archives: Pulsed Xenon UV Room Disinfection System

Mayo Clinic Pulsed Xenon UV Room Disinfection Study Reports 47% Reduction in C.diff. Infection Rates

 

Even with the world’s most robust infection prevention strategy and protocols, the Mayo Clinic wanted to further reduce its patients’ risk for contracting C.diff and conducted a controlled study to evaluate the effectiveness of Xenex Disinfection Systems’ pulsed xenon ultraviolet (UV) light room disinfection technology. The study, published in the American Journal of Infection Control, found that adding pulsed xenon UV disinfection to the hospital’s disinfection efforts resulted in a 47% reduction in C.diff infection rates on the intervention units that has been sustained for two years. In addition, the facility saw an increase in patient satisfaction scores for environmental cleanliness and a 52% reduction in Vancomycin-resistant enterococci (VRE) infection rates.

Based on the significant C.diff infection rate reductions in the intervention units, the Mayo Clinic expanded pulsed xenon UV room disinfection to 14 additional hospital units with high rates of C.diff infection utilizing 12 robots. This wide-scale implementation resulted in a facility-wide reduction in its Standardized Infection Rate (SIR) from 0.774 to 0.571. SIR rates are used by the Centers for Medicare & Medicaid Services (CMS) to calculate hospital reimbursement.

Many hospital patients, especially those on antibiotics, are susceptible to C.diff, which can live for up to five months on surfaces in the hospital. A person with C.diff may contaminate their hospital room and bathroom, leaving C.diff spores on the walls, handles and other high-touch surfaces. These spores can be easily transferred to the next patient or healthcare worker in that room. For this study, the Mayo Clinic deployed two Xenex LightStrike™ Germ-Zapping Robots™ that utilize intense pulsed xenon UV light to quickly destroy pathogens like C.diff and VRE that may be lurking on high-touch surfaces in a room, such as bedrails, tray tables and doorknobs. The robot is easy to use and does not require warm-up or cool-down time, so it’s easily transported from room to room.

In the controlled trial, the first of its kind using pulsed xenon UV disinfection technology, three hospital units (two hematology and bone marrow transplant units and one medical-surgical unit) were designated for pulsed xenon UV intervention, and three units with similar patient populations served as control units. Because of the high C.diff infection rates, all patient rooms on the targeted units were cleaned with bleach daily and at terminal cleaning. In addition to tracking C.diff infection rates, hand hygiene, isolation compliance, and antimicrobial usage were followed on all the units. The only difference in the infection control programs between the controlled units and intervention units was the addition of LightStrike pulsed xenon UV disinfection. LightStrike robots were used after terminal cleaning in 85% of all discharges on the targeted intervention units.

“The Mayo Clinic has a world class infection prevention program that is extremely well-run and well monitored. Their success in reducing C.diff rates is strong evidence that pulsed xenon UV room disinfection can be a very effective tool in a hospital’s infection prevention bundle,” said Dr. Mark Stibich, Chief Scientific Officer at Xenex. “This is very exciting research for several reasons. First, the hospital achieved and sustained lower C.diff rates. Second, hospitals may be confused about the different kinds of UV technologies and their effectiveness, especially after a previous study using mercury UV devices did not show a reduction in C.diff infection rates. This data – and the story of how the Mayo Clinic achieved success in a controlled trial – demonstrates that Xenex’s pulsed xenon UV disinfection technology should be added to the infection prevention bundle as standard of care to enhance patient safety.”

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CLINICAL TRIAL IN PROGRESS 

Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated Infection

Recruitment Status : Recruiting

First Posted : November 21, 2017
Last Update Posted : November 27, 2018

ClinicalTrials.gov Identifier: NCT03349268

Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03349268

 

Contacts
Contact: Keith S. Kaye, MD, MPH 734-615-1901 keithka@med.umich.edu
Contact: Jolene E Daniel 734-615-1901 jolened@med.umich.edu

 

Locations
United States, Michigan
Detroit Medical Center Recruiting
Detroit, Michigan, United States, 48205
Contact: Paul Kilgore, MD    313-577-1215    paul.kilgore@wayne.edu
Sponsors and Collaborators
University of Michigan
Agency for Healthcare Research and Quality (AHRQ)
Xenex Disinfection Services LLC
Detroit Medical Center
Henry Ford Health System
TEMPVA Research Group, Inc.
Wayne State University
Investigators
Principal Investigator: Keith S. Kaye, MD, MPH University of Michigan

STUDY DESCRIPTION:

Brief Summary:

The objective is to conduct a prospective, sham controlled, double-blinded, interventional crossover trial to compare standard terminal cleaning plus PX-UV (intervention) with standard terminal cleaning plus sham PX-UV (control) with crossover at 12 months, following a 6-month washout period. Outcome measures include the rates of HAIs, as well as the recurrence of genetically identical clinical strains of HAIs among patients on study units. The study will be conducted in 2 hospitals covering 16 total hospital units at Detroit Medical Center. Our central hypothesis is that the addition of PX-UV to standard terminal cleaning will be associated with a significant reduction in the rate of HAIs, as well as a reduction in the recovery of genetically identical strains of MDROs. The impact of PX-UV disinfection on rates of HAIs on study units will be determined by comparing rates of HAIs on a) study units where PX-UV is added to standard terminal cleaning practices to b) units where a sham UV disinfection system is added to standard terminal cleaning; and by comparing rates of HAIs on the same medical ward during each of two 12-month phases of a crossover study (one phase when a PX-UV device is added and one when a sham device is added to standard terminal cleaning).

The long-term goal of this project is to establish the efficacy of terminal cleaning plus PX-UV in reducing rates of HAIs due to the following multi-drug resistant organisms (MDROs): C. difficile, vancomycin-resistant enterococci (VRE), Klebsiella pneumoniae and Escherichia coli producing extended-spectrum beta-lactamases (ESBLs), methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii.

At the conclusion of the proposed project, novel data will be generated from this rigorously controlled study regarding the effectiveness of PX-UV in reducing HAIs in a representative, real-world healthcare setting.

To learn more about this Clinical study in progress – please click on the following link to be redirected to clinicaltrials.gov

https://clinicaltrials.gov/ct2/show/NCT03349268?cond=Clostridium+Difficile&draw=5&rank=240

 

 

Xenex Disinfection Services’ LightStrike™ Robot With Pulsed Xenon Ultraviolet-C (UV-C) Light Technology Introduces Its LightStrike Disinfection Pod

The scientific evidence has clearly established that in the hospital environment, microorganisms such as Clostridium difficile (C.diff), Methicillin-resistant Staphylococcus aureus (MRSA) and carbapenem-resistant Enterobacteriaceae (CRE) are responsible for the infections that kill nearly 300
people in the U.S. every day.

Xenex Disinfection Services’ LightStrike™ Robot with pulsed xenon ultraviolet-C (UV-C) light technology is a proven solution that quickly destroys deadly viruses, bacteria and spores before they pose a threat to patients and healthcare workers. LightStrike Robots help healthcare facilities reduce their HAI rates by destroying the microscopic germs that may be missed during the manual cleaning process. Xenex robots use pulsed xenon, a noble gas, to create Full Spectrum™, high intensity UV light that quickly destroys infectious germs in less than five minutes. Hospitals using Xenex devices have published clinical outcome studies in peer-reviewed journals showing 50-100 percent reductions in C.diff, MRSA and Surgical Site Infection rates when those hospitals used LightStrike Robots to disinfect rooms.

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Now, for the first time, hospitals can utilize the power of

LightStrike Germ-Zapping Robots™ to quickly disinfect mobile equipment just as effectively as they disinfect rooms within their facility. Pathogens like C.diff, Acinetobacter baumannii, MRSA and Vancomycin-Resistant Enterococci (VRE) can travel throughout a healthcare facility on mobile equipment.

To address this gap in the infection control process, Xenex recently partnered with an industry leader in containment units, Mintie Technologies, Inc., to create the LightStrike Disinfection Pod.

Designed to quickly disinfect reusable mobile equipment such as isolettes, ventilators, pressure monitors, wheelchairs and workstations, the

LightStrike Disinfection Pod enables the power of the LightStrike Robot’s intense, germicidal light to be used anywhere in a facility.
The Pod is collapsible, mobile and can be positioned in a hospital hallway or other areas without disrupting or impeding daily workflow. Its proprietary design integrates reflective interior fabric ensuring 360 degrees of UV light coverage over difficult-to-clean equipment including anesthesia carts, ventilators, and mobile imaging machines.

To access and read the article in its entirety please click on the link below:

https://www.dotmed.com/news/story/37771

6th Graders Receive Up Close and Personal Education with a Light-Pulsing, Disinfecting Robot

Sharing and Educating

Opening eyes of the young with disinfecting

technology being utilized to combat “superbugs.”

 

The only robot in the Verdugo region that zaps away unwanted bacteria and viruses from hospital rooms arrived at USC-Verdugo Hills Hospital two weeks ago.

The Xenex robot emits a pulsating, bright white UV-C light — which is a short, wavelength, ultraviolet light that can save lives. Once surfaces are exposed to the robot’s rays, harmful bacteria and viruses die, greatly reducing the odds patients will be infected with hospital-acquired infections, including those caused by superbugs such as methicillin-resistant Staphylococcus aureus, known as MRSA.

USC-Verdugo Hills Hospital employees joined Xenex employees at Fremont Elementary School, where they showcased the $100,000 machine in teacher Mallory Kane’s sixth-grade classroom, the same place where Keith Hobbs, chief executive of Verdugo Hills Hospital, was a sixth-grader in 1979. “There’s no other place that I would rather be than to come back to my alma mater and share this R2D2, bug-zapping machine with you guys,” Hobbs said.

The Xenex robot pulses UV-C light 67 times per second, and hospital staff take precautions when they operate it because the light can harm their eyes.

“This is not any light bulb in your house,” said Mary Virgallito, director of patient safety for the hospital. “It’s actually filled with a gas called xenon.”

Virgallito said hospital employees manually clean rooms before they activate Xenex. It takes the robot about 15 minutes to clean a patient’s room, and 20 minutes to disinfect an operating room.Hobbs said mothers ask if they can borrow the robot to disinfect their own homes, and Kane suggested it would be helpful in the classroom. Over the past several weeks, many of her students missed school because they were sick.

Jeff Mamalakis, business development manager for Xenex, volunteered to disinfect Kane’s room when school let out. The space would be left with a scent as if lightning had just struck, Virgallito said.  The impromptu high-tech, germ-cleansing session was a dream come true for Kane.

“In sixth grade, the curriculum moves so quickly that even missing one day puts kids so far behind,” Kane said. “Having our classroom disinfected every day would be a dream come true. My kids would be here, everyone would be happy, no one would have to miss school.”

To Read the article in its entirety please click on the following link:

http://finance.yahoo.com/news/uhc-most-xenex-germ-zapping-144500378.html;_ylt=A0LEV18lQNBY2KgA6FZXNyoA;_ylu=X3oDMTEzMXBobHNmBGNvbG8DYmYxBHBvcwMxBHZ0aWQDVUkwMkM0XzEEc2VjA3Nj

Cdiff Spores and More With Dr. Mark Stibich Discuss Healthcare-associated Infections Being Successfully Eliminated By Xenex Germ Zapping Robots, UV Disinfection Services

 

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C. diff. Spores and More,” Global Broadcasting Network – innovative and educational interactive healthcare talk radio program discusses

This episode——

“Xenex Germ Zapping Robots, UV Disinfection Services”

With Our Guest:       Dr. Mark Stibich, PhD

Join us as guest, and co-founder of Xenex, Dr. Mark Stibich Epidemiologist and Chief Scientific Officer, discusses UV Disinfection with Xenex UV Disinfecting Systems and Germ Zapping Robots making a clean sweep across the globe zapping ‪‎C.diff‬. and all harmful germs that can cause pain, suffering, and double digits in the already stressed healthcare industry.

 

MORE ABOUT OUR GUEST:

Dr Mark Stibich, a co-founder of Xenex, Mark oversees scientific research, new technology development, and protocol design. An epidemiologist who has published many scientific papers about Pulsed Xenon technology, Mark is also an inventor on multiple patents. Originally from Dayton, OH, Mark graduated from Yale and the Johns Hopkins University School of Public Health, where he earned a Masters in Health Science and PhD.  Mark’s interest in public health has taken him to many distant countries. He served as a Peace Corps health volunteer and then trained Peace Corps health volunteers in Ulaanbaatar, Mongolia. He has conducted research in Russia, Tajikistan, Afghanistan, South Africa, Kenya, the U. S., and Brazil. In addition, he has received grants for and directed HIV/AIDS research and intervention projects throughout Russia and has been a consultant with the USAID project.

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community and more.

Through their interviews, the C Diff Foundation mission will connect, educate, and empower many worldwide.

Questions received through the show page portal will be reviewed and addressed  by the show’s Medical Correspondent, Dr. Fred Zar, MD, FACP,  Dr. Fred Zar is a Professor of Clinical Medicine, Vice HeZarPhotoWebsiteTop (2)ad for Education in the Department of Medicine, and Program Director of the Internal Medicine Residency at the University of Illinois at Chicago.  Over the last two decades he has been a pioneer in the study of the treatment of
Clostridium difficile disease and the need to stratify patients by disease severity.

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Xenex’s xenon light Germ-Zapping Robots™ Decrease Infection Rates Significantly At Orlando Florida Health South Seminole Hospital

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Infection rates decreased significantly at Orlando Health South Seminole Hospital after the hospital began using Xenex’s xenon light Germ-Zapping Robots™ for room disinfection, according to a new peer-reviewed study published in the American Journal of Infection Control (AJIC). This is the eighth peer-reviewed study that demonstrates how a hospital successfully reduced its infection rates after utilizing Xenex Disinfection Services’ unique Xenon Full-Spectrum Disinfection™ technology to disinfect its rooms. Xenex Germ-Zapping Robots™ have been credited for helping healthcare facilities in the U.S. decrease their Methicillin-resistant Staphylococcus aureus (MRSA), Clostridium difficile (C.diff) and Surgical Site infection rates by more than 50, 70 and 100 percent respectively.

Xenex’s xenon light disinfection system is the only disinfection system that uses pulsed xenon to create light that covers the entire germicidal spectrum. The Xenex system is the only ultraviolet light disinfection technology shown, in multiple peer-reviewed published studies, to help hospitals reduce infection rates.

According to the new AJIC study, South Seminole Hospital reported a 61 percent reduction in combined Vancomycin-resistant enterococci (VRE), MRSA and C.diff infection rates in its Intensive Care Unit (ICU), an 87 percent reduction in its ICU VRE infection rate, and a 29 percent reduction facility-wide in combined VRE, MRSA and C.diff infection rates after it began using Xenex’s xenon light technology. The hospital estimates that it saved $730,000 based on the number of C.diff and VRE infections that were avoided.

The study titled “Impact of pulsed xenon ultraviolet light on hospital-acquired infection (HAI) rates in a community hospital” analyzed the efficacy of pulsed xenon light in two different deployment strategies.

The difference in infection rate reduction was associated with the two different utilization strategies, which indicates best practices for pulsed xenon disinfection. ICU discharges and transfers were disinfected with Xenex Germ-Zapping Robots with a goal of all terminal cleans.

As a result, the combined VRE, MRSA and C.diff infection rates decreased 61 percent. Non-ICU discharges and transfers were disinfected with Xenex robots for C.diff cases only, resulting in a 29 percent decrease in VRE, MRSA and C.diff infection rates facility wide.

“This is an exciting study because it demonstrates best practices for pulsed xenon automated disinfection,” said Dr. Mark Stibich, Chief Scientific Officer at Xenex. “Previous studies have shown that the number of rooms disinfected with the Xenex robot correlates to the infection rate reduction the hospital will experience. This study shows that it’s more effective to use the Xenex robot to disinfect as many rooms as possible versus only disinfecting rooms where patients are known to have an infection. Our pulsed xenon robot works in a five-minute disinfection cycle, so they are able to quickly disinfect multiple rooms per day in a facility – leading to dramatic reductions in infection rates.”

Designed for speed, effectiveness and ease of use, hospital cleaning staff operate the Xenex robot without disrupting hospital operations. The robot pulses intense UV light covering the entire UV spectrum, destroying viruses, bacteria and bacterial spores in a five-minute disinfection cycle. Without contact or chemicals, the robot eliminates harmful microorganisms safely and effectively. According to Xenex customers, the robot can disinfect 30-62 hospital rooms per day, including: patient rooms, operating rooms, equipment rooms, emergency rooms, intensive care units and public areas.

Proven to Reduce HAI Rates

MD Anderson Cancer Center, the Central Texas Veterans Health Care System, Cooley Dickinson Health Care, Trinity Medical Center and other hospitals have published 14 studies providing evidence of the robot’s efficacy in highly regarded scientific journals that include the American Journal of Infection Control (AJIC), Journal of Infection Prevention, Infection Control & Hospital Epidemiology (ICHE) and BMC Infectious Diseases.

About Xenex Disinfection Services

Xenex’s patented Full Spectrum™ pulsed xenon UV room disinfection system is used for the advanced disinfection of healthcare facilities. Due to its speed and ease of use, the Xenex system has proven to integrate smoothly into hospital cleaning operations. The Xenex mission is to save lives and reduce suffering by eliminating the deadly microorganisms that cause HAIs. The company is backed by well-known investors that include Brandon Point, Battery Ventures, Targeted Technology Fund II and RK Ventures. For more information, visit www.xenex.com.

 

Resource:

http://www.businesswire.com/news/home/20160301006521/en/Infection-Rates-Decline-Florida-Hospital-Xenex-Germ-Zapping