Tag Archives: CDC Antibiotoc Resistance

Thanks and Appreciation To Our Guests For Joining Us On C. diff. Spores And More Season II


As Season II concludes, we wish to take this opportunity to sincerely thank each
and every guest for taking time out of their
busy schedule and joining us on Tuesday’s at
10:00a Pacific Time / 1:00p Eastern Time over the past seven months.

C. diff. Spores and More Global Broadcasting Network will be taking a break and will return to live broadcasting on  January 17th, 2017 with the Centers for Disease Control and Prevention (CDC) leading the way with our guest
Dr. Katherine Fleming-Dutra, Medical Officer, CDC’s Office of Antibiotic Stewardship.

A Prescription for Over-Prescribing: The Key to Fighting
Antibiotic Resistance

Dr. Fleming-Dutra is a medical epidemiologist with the Office of Antibiotic Stewardship in the Division of Healthcare Quality Promotion at the Centers Disease Control and Prevention (CDC).

Dr. Fleming-Dutra is a pediatrician and pediatric emergency medicine physician and has focused on infectious diseases epidemiology and antibiotic stewardship in the outpatient setting in her career at CDC.

Join Dr. Fleming-Dutra as she discusses a recent study published by the Journal of the American Medical Association, was released showing that at least 30 percent of all prescriptions written in doctors’ offices and emergency rooms are completely unnecessary. So how do we use these alarming results to transform the culture of over-prescribing Dr. Katherine Fleming-Dutra, M.D., will:

  • Give a detailed explanation of the study results, and provide an in-depth review of specific findings;
  • Highlight what CDC is doing to promote antibiotic stewardship across healthcare settings, and
  • Identify what clinicians, other health care professionals, and patients can do to improve antibiotic prescribing, therefore fighting antibiotic resistance.


C diff Radio Live Broadcast AND Podcasts

C. diff. Spores and More Global Broadcasting Network

  brought to you by VoiceAmerica and
sponsored by Clorox Healthcare

An educational program that is dedicated to  C. difficile Infections  and more–


Click On The LOGO  Above And Enjoy Listening To the Live Broadcasts In the C. diff. Spores and More Podcast Library.


Live Broadcast airs
on Tuesdays at:    10a PT,    11a MT,   12p CT,    1p ET

We are pleased to share  “C. diff. Spores and More ”  with you because, as advocates of  C. diff.,  we know the importance of this cutting-edge new weekly radio show  and what it means for our Foundation’s community worldwide.–

Hard Facts: Deaths and illnesses are much higher than reports have shown. Nearly half a million Americans suffered from Clostridium difficile (C. diff.) infections in a single year according to a study released today, February 25, 2015, by the Centers for Disease Control and Prevention (CDC).

• More than 100,000 of these infections developed among residents of U.S. nursing homes.

Approximately 29,000 patients died within 30 days of the initial diagnosis of a C. diff. infection. Of these 29,000 – 15,000 deaths were estimated to be directly related to a
C. diff. infection. Therefore; C. diff. is an important cause of infectious disease death in the U.S.

Previous studies indicate that C. diff. has become the most common microbial cause of Healthcare-Associated Infections found in U.S. hospitals driving up costs to $4.8 billion each year in excess health care costs in acute care facilities alone. Approximately
two-thirds of C. diff. infections were found to be associated with an inpatient stay in a health care facility, only 24% of the total cases occurred in patients while they were hospitalized. The study also revealed that almost as many cases occurred in nursing homes as in hospitals and the remainder of individuals acquired the
Healthcare-Associated infection, C. diff., recently discharged from a health care facility.

This new study finds that 1 out of every 5 patients with the Healthcare-Associated Infection (HAI), C. diff., experience a recurrence of the infection and 1 out of every 9 patients over the age of 65 diagnosed with a HAI – C. diff. infection died within 30 days of being diagnosed. Older Americans are quite vulnerable to this life-threatening diarrhea infection. The CDC study also found that women and Caucasian individuals are at an increased risk of acquiring a C. diff. infection. The CDC Director, Dr. Tom Frieden, MD, MPH said, “C. difficile infections cause immense suffering and death for thousands of Americans each year.” “These infections can be prevented by improving antibiotic prescribing and by improving infection control in the health care system. CDC hopes to ramp up prevention of this deadly infection by supporting State Antibiotic Resistance Prevention Programs in all 50 states.”

“This does not include the number of C. diff. infections taking place and being treated in other countries.”  “The  C Diff Foundation supports hundreds of communities by sharing the Foundation’s mission and  raising C. diff. awareness to healthcare professionals, individuals, patients, families,  and communities working towards a shared goal ~  witnessing a reduction of newly diagnosed C. diff. cases by 2020 .”   ” The C Diff Foundation volunteer Advocates are greatly appreciated and continue to create positive changes by sharing their time  aiding in the success of our mission “Raising C. diff. awareness ”  worldwide.

C. diff. Spores and More “ spotlights world renowned topic experts, research scientists, healthcare professionals, organization representatives, C. diff. survivors, board members, and their volunteers who are all creating positive changes in the
C. diff.
community and more.

Through their interviews, the C Diff Foundation mission will connect, educate, and empower listeners worldwide.

Questions received through the show page portal will be reviewed and addressed  by the show’s Medical Correspondent, Dr. Fred Zar, MD, FACP,  Dr. Fred Zar is a Professor of Clinical Medicine, Vice Head for Education in the Department of Medicine, and Program Director of the Internal Medicine Residency at the University of Illinois at Chicago.  Over the last two decades he has been a pioneer in the study of the treatment of Clostridium difficile disease and the need to stratify patients by disease severity.


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Programming for C. diff. Spores and More  is made possible through our official Corporate Sponsor;  Clorox Healthcare

We look forward to sharing time with our worldwide listeners when we return in January, Season III. 

Until then………………

We send out get-well wishes to everyone being treated for and recovering from a C. difficile infection and all wellness draining illnesses worldwide.

“None of us can do this alone – All of us can do this together!”

Antibiotic Stewardship Program and Updates From Sources: CDC, Pew Charitable Trusts, With IDSA and SHEA Guidelines

Antibiotic Stewardship Information and Update:

Inpatient antibiotic stewardship programs (ASPs) lower rates of healthcare-associated infections, increase microbial susceptibility to antibiotics, and save healthcare costs, according to ten case studies published in an Apr 26 report from the Pew Charitable Trusts (PCT).

“All antibiotic use contributes to the proliferation of antibiotic-resistant bacteria, and more than 2 million people are infected with antibiotic-resistant organisms each year in the United States, resulting in more than 23,000 deaths,” the 63-page report says. The US Centers for Disease Control and Prevention (CDC) released a report in 2013 estimating that about half of antibiotics prescribed each year are unnecessary.

To listen to the February 2016 Podcast: Using Antibiotics Wisely, How You Can Help In the Fight Against Antibiotic Resistance — with Doctors Laurie Hicks and Arjun Srinivansan from the CDC — click on the link below:


ASPs curb inappropriate antibiotic prescriptions with clinician education, better matching of antibiotics to infections (bug-drug matches), and rigorous authorization protocols for prescriptions, yet often are met with some resistance due to funding insufficiency, lack of dedicated staff or laboratory capability, and changes in accepted standards of care.

PCT’s report, “A Path to Better Antibiotic Stewardship in Inpatient Settings,” describes ASPs in five community hospitals, three academic hospitals, and two long-term care facilities. Each had incorporated all seven of the CDC’s “Core Elements of Hospital Antibiotic Stewardship”: leadership commitment, accountability, drug expertise, action (eg, systems to monitor treatment and bug-drug matches), education, tracking, and reporting.

To review the updated IDSA and SHEA “Antibiotic Stewardship” Guidelines please click on the link below:



All except an academic hospital with a 20-year history of antibiotic stewardship interventions implemented their programs between 2006 and 2011. Though all demonstrated significant leadership and commitment to the interventions, each facility used practices and technology specific to their patient populations, outbreak history, staff availability, and lab capacity.

Administrative and physician support for stewardship

Outbreaks and high rates of healthcare-associated infections spurred operational support and funding for ASPs in four facilities, according to the report. Vibra Hospital of Northern California in Redding, Calif., and Sharp Villa Coronado Long-Term Care Facility in Coronado, Calif., were able to obtain support for nascent ASPs after linking antibiotic use to increases in healthcare-associated Clostridium difficile (C diff) infections.

Park Manor Nursing Home in Park Falls, Wis., and St. Tammany Parish Hospital in Covington, La., instituted their protocols after an outbreak of methicillin-resistant Staphylococcus aureus (MRSA) and an increase in infections after coronary artery bypass grafts, respectively.

Blessing Hospital in Quincy, Ill., received institutional approval for an ASP after demonstrating the need for stewardship with a 4-month study on inappropriate use of aztreonam, tigecycline, daptomycin, and linezolid.

Staff roles and laboratory capacity

Most ASPs were led by at least one infectious disease or family practice physician and pharmacist who dedicated several hours per week to monitoring prescriptions and effectiveness of antibiotic treatment, the report explains. Exceptions were the program at Sharp Villa Coronado Long-Term Care Facility, which was led by pharmacists and pharmacy students, and the nurse-led ASP at Park Manor Nursing Home.

Because Park Manor had neither an on-site physician nor a pharmacist, nurses maintained detailed reports of patient infections, bacterial culture results, and antibiotic use, and then developed scripts to communicate patient status and care to physicians. The use of nursing staff to shepherd stewardship efforts, carry out active surveillance for urinary and respiratory tract infections, and communicate between patients and doctors reduced the number of unnecessary prescriptions, the authors said.

Both long-term care facilities were able to perform simple lab tests but had to send samples off-site for more complex testing and culturing. Several community hospitals lacked the ability to conduct on-site and/or rapid diagnostic testing and culturing, which increased waiting time for decisions about antibiotic therapy.

Lowering antibiotic use and infections

Ongoing treatment monitoring and patient interventions had the most measurable effects on inappropriate antibiotic use, the report states. Vibra Hospital found that changes to antibiotic regimens were needed in all 93 patient cases it monitored from May to June 2015. Vibra clinicians worked with the ASP to schedule antibiotic treatment stop dates for 46 patients, discontinue treatment for 42, review cultures and assign new prescriptions in 10 cases, and change four dosages because of new information on weight or kidney function.

Sharp Villa’s implementation of an antibiotic dosing protocol to prevent renal toxicity and ongoing therapy assessment lowered antibiotic use by 59%, with significant decreases in broad-spectrum antibiotics, vancomycin, antifungals, and C diff therapies. From 2011 to 2015, Escherichia coli susceptibility to levofloxacin at Sharp Villa rose from 24% to 54%.

Several facilities saw decreases in healthcare-associated C diff rates after ASP implementation. After educating physicians on substitutes for restricted or nonformulary antibiotics and transitions from intravenous to oral therapy, Williamson Medical Center in Franklin, Tenn., observed C diff rates fall from 26.3 infections per 10,000 patient-days in 2013 to 21.1 cases per 10,000 patient-days in 2014. At the same facility, the susceptibility of Pseudomonas aeruginosa to levofloxacin increased from 58% in 2009 to 79% in 2014.

St. Tammany’s antibiotic treatment surveillance and training interventions led to a fall in C diff rates from 9.6 per 10,000 patient-days in 2013 to 6.4 in 2014. Through active surveillance and close physician-pharmacist partnerships, the hospital was also able to reduce daily doses of daptomycin by 84%, linezolid by 79%  tigecycline by 86%, and micafungin by 61%, and lowered total antimicrobial costs from $25.93 to $8.32 per patient-day.

The University of California, Davis Medical Center’s focus on prescription audits, bug-drug mismatches confirmed by culture, yeast colonization of sterile sites, and vancomycin resistance yielded a 23% reduction in C diff rates, which saved an estimated $23,540 in costs. Prescription decreases for 11 antibiotics targeted for intervention by the facility’s ASP led to cost savings of about $119,009 since the program began in 2011.

Opportunities and challenges

In most cases, ASPs at the 10 facilities proved effective when procedures were automated and when continual communication about antibiotic therapy was maintained between clinicians, pharmacists, and lab staff, according to the report. For example, Strong Memorial Hospital in Rochester, N.Y., held weekly antibiotic stewardship rounds between ASP members and six clinical services. Three hospitals observed increasing clinician acceptance of pharmacists’ prescribing recommendations over the course of their programs.

Barriers noted by some of the hospitals and centers included lack of dedicated staff time and funding for technology, including electronic health records in long-term care centers, that would more closely track patient therapies.

A recent action plan from the Obama administration proposed that all acute care hospitals and long-term care facilities implement ASPs, and California recently made it a requirement for acute care hospitals. Given the trend toward formalizing antibiotic stewardship and the benefits such programs can yield for patient care, microbial susceptibility, and facility costs, these case studies offer diverse methods and results to help burgeoning programs evaluate ASP feasibility in their institutions, the report says.

To read article in its entirety – click on the link below:


Patient Safety With The Centers for Disease Control and Prevention (CDC) Surveillance Antibiotic Resistance Patient Safety Atlas and More

P A T I E N T   S A F E T Y 

CDC’s Antibiotic Resistance Patient Safety Atlas provides open and interactive data about healthcare-associated infections (HAIs) caused by antibiotic resistant bacteria, which are reported to CDC through the National Healthcare Safety Network (NHSN).

You can customize maps and tables to show antibiotic resistance patterns in Healthcare-Associated Infections (HAI’s)  by filtering the data by geographical area (national, regional, and state), time period, event type, and patient age.

For more information visit the following CDC Website:


Using Antibiotics Wisely, How Everyone Can Help In the Fight Against Antibiotic Resistance Worldwide

Did you have the opportunity to listen  to the live broadcast on “C. diff. Spores and More Global Broadcasting Network”  on Tuesday, February 9th, 2016 with guests Dr. Lori Hicks and Dr. Arjun Srinivasan from  the Centers of Disease Control and Prevention (CDC) ?

Dr. Hicks and Dr. Srinivasan discussed how to use antibiotics wisely and how everyone can help in the fight against antibiotic-resistance.

This important  information  is now available to you on demand by clicking directly on the logo below


For additional information on Inpatient Antibiotic Stewardship please click on the following link:



To access the CDC Get Smart Program, please click on the following link to be redirected:




C. diff. Spores and More” programming is brought to you by VoiceAmerica  and sponsored by Clorox Healthcare

For more information please visit the C. diff. Spores and More program page:


C diff Spores and More Global Broadcasting Network and Guests Dr. Srinivasan and Dr. Hicks of the CDC Discuss Antibiotic Resistance

C. diff. Spores and More , Global Broadcasting Network – innovative and educational interactive healthcare talk radio show discuss antibiotic resistance and what everyone can do to join in the fight against it with guests Dr. Arjun Srinivasan and
Dr. Lauri Hicks on Tuesday, February 9th at 10 AM Pacific Time on VoiceAmerica Health and Wellness Channel

Bringing guests together, such as Dr. Arjun Srinivasan, MD and Dr. Lauri Hicks, DO from the Center of Disease Control and Prevention (CDC), one of the leading government healthcare organizations in the U.S., and internationally recognized experts on antibiotic resistance has built a loyal listenership and continue to inform and educate listeners’ worldwide.

C.diff. Spores and More” is broadcast live every Tuesday at 10 AM Pacific Time on the VoiceAmerica Health and Wellness channel, officially sponsored by Clorox Healthcare. Archived C. diff. Spores and More shows can be found Here.

“I am so proud to be the Senior Executive Producer of the “C. diff. Spores and More,” program as it continues to raise awareness, on a global level, of the overuse of antibiotics. Having guests; Dr. Arjun Srinivasan, MD and Dr. Lauri Hicks, DO truly affect change in both the leadership and education guiding the public and raising awareness in many areas of health care,” stated Robert Ciolino, Senior Executive Producer VoiceAmerica.

About The C diff Foundation Executive Director
Nancy C Caralla, hosts “C. diff. Spores and More” Global Broadcasting Network with a team focus on educating, and advocating for C. diff. infection prevention, treatments, and environmental safety – and more — worldwide.

For information please visit www.cdifffoundation.org

Listen in on Tuesday, February 9th at 10:00 Pacific Time–